Overview of the Meeting
September 7-10, 2016
Banff, Alberta, Canada
The ISACB meeting comes to beautiful Banff Alberta for its first ever meeting in Canada! Join clinicians, engineers, and scientists from academia, government and industry in Banff to hear about the latest advances and network with the community.
The meeting theme for this year is Transforming Approaches to Cardiovascular Health and Disease: Enabling Biology and Engineering in Prevention, Diagnosis, Therapeutics and Devices.
This conference provides a forum for cardiovascular professionals working in academia, industry and clinics to convene to disseminate new information in their fields, build relationships with one-another and establish strategies for translating advancements. The focus of the conference will be upon translation of basic research including stem cells, tissue interactions and cardiovascular biomaterials and novel cardiovascular diagnostics, imaging and therapeutics. A dedicated plenary session will focus upon issues related to technology translation and commercialization.
Webinar Preview featuring the Programming and Local Chairs of 15th Biennial ISACB Meeting
Podcast Preview of 15th Biennial ISACB Meeting featuring Dr. Paul Fedak and ISACB President Dr. David Vorp
About the Banff Centre
The Banff Centre is the largest arts and creativity incubator in the world. Founded in 1933, its mission is inspiring creativity. This world-renowned conference centre is nestled on the side of Tunnel Mountain in Banff National Park, a UNESCO World Heritage Site in the heart of the Canadian Rockies. Its specialized retreat-like setting, and unique learning environment allow the focus to be directed on achieving results, yet it’s just minutes from the activities and amenities of an international tourism destination. Every year, more than 500 conferences are held at The Banff Centre. The world’s most influential leaders, researchers, and educators, gather here to think dynamically, and to invent the future. The Banff Centre is the ideal place to inspire creativity.
Local Organizing Committee
Kristina Rinker, PhD, PEng, (Chair), Director and Associate Professor, Centre for Bioengineering Research and Education, University of Calgary
Elena Di Martino, PhD, PEng, Associate Professor, Centre for Bioengineering Research and Education, University of Calgary
Paul Fedak, MD, PhD, Associate Professor, Department of Cardiac Sciences, Cardiac Surgeon, Alberta Health Services, Director, Marlene and Don Campbell Translational Research Laboratory, University of Calgary, Adjunct Associate Professor, Northwestern University, Chicago, USA
Randy Moore, MD, MSc, Associate Professor, University of Calgary
Glenn Gaudette, PhD (Lead-Overall and Industry/Translation), Worcester Polytechnic Institute, Worcester, MA
Luke Brewster, MD, PhD (Lead, Clinical), Emory University School of Medicine, Atlanta, GA
Elena Aikawa, MD, PhD (Lead-Basic Research), Brigham & Women’s Hospital, Harvard Medical School, Boston, MA
Jane Grande-Allen, PhD (Lead-Trainees/Early Career), Rice University, Houston, TX
Fred Schoen, MD, PhD (Advisor), Brigham & Women’s Hospital, Harvard Medical School, Boston, MA
Julie Phillippi, PhD (Lead-Meeting Podcasts), University of Pittsburgh, Pittsburgh, PA
Gala Keynote Speaker - Friday September 9, 2016
Stuart Hutchison MD, FRCPC, FACC, FAHA, FASE, FSCMR, is a Clinical Professor of Medicine in the Departments of Cardiac Sciences, Internal Medicine, and Radiology at the University of Calgary, and is a member of the Libin Institute and Stephenson Cardiovascular MRI Center.
He was educated in Cardiology at McGill University, acquired further sub-specialty training at the University of Southern California and at vascular physiology / pharmacology research fellowship at the CardioVascular Research Institute of the University of California at San Francisco. He was the Director of Echocardiography at St. Michael’s Hospital at the University of Toronto for a decade before moving to Calgary in Calgary in 2008.
He has written 80 articles, 15 book chapters, 72 abstracts, and 7 books with an 8th book in development, with interests in aortic diseases, pericardial diseases, complications of infarction, and multi-modality cardiac imaging. He has received Provincial Excellence in Teaching awards (PAIRO and PAIRA).
An avid sportsman, he has run twenty marathons, cycled through Europe and climbed the tallest peaks in the world across three continents. Having scaled the likes of K2 and having been within a few hundred feet of the summit of Mount Everest on his second expedition there, he points to some of the tallest in North America as his favorites and the scaling of Cho Oyo, the sixth tallest worldwide, as the most satisfying.
Benjamin W. Starnes, M.D. FACS
Alexander Whitehill Clowes, MD Endowed Chair in Vascular Surgery
Professor and Chief, Division of Vascular Surgery
Vice Chair, Department of Surgery
Dr. Starnes is a Professor of Vascular Surgery, Chief of the Division of Vascular Surgery and Vice Chair of the Department of Surgery for UW Medicine. He is recognized nationally and internationally for his work in aortic pathology and vascular trauma, most notably the management of ruptured abdominal aortic aneurysms and acute aortic syndromes.
Dr. Starnes received his undergraduate degree at Albright College in Reading, PA, his medical degree at Jefferson Medical College in Philadelphia and completed his surgical training at Walter Reed in Washington, D.C. Prior to accepting his position at the UW, Dr. Starnes spent a total of 15 years in the United States Army serving three combat tours, one in Kosovo and two in Iraq.
Dr. Starnes’ current research activities focus on multi-branch and fenestrated endografting for complex aortic disease, vascular trauma and studying factors that influence outcomes for patients presenting with ruptured abdominal aortic aneurysm. He currently serves as Principal Investigator on ten clinical trials and as Associate Investigator on an additional twenty-two clinical trials. Dr. Starnes’ extensive research involvement combined with his clinical and technical abilities provides him with opportunities to speak regularly at medical conferences around the globe. He has accepted fifteen national visiting professorships and lectured internationally in thirteen different countries including France, Belgium, Australia, the United Kingdom, Brazil and China.
In addition to clinical and research activities, Dr. Starnes is highly involved in the academic community of vascular surgery. He has been author or co-author of over eighty peer-reviewed publications with a quarter as first author and written five book chapters. Dr. Starnes’ editorial review responsibilities with the leading vascular journals include The Journal of Vascular Surgery, Circulation, New England Journal of Medicine and Lancet. He is an active member of Western Vascular Society, Western Surgical Association and the Society for Vascular Surgery and current President of the Pacific Northwest Vascular Surgery Society. In addition he served as an Associate Examiner of the American Board of Surgery Vascular Surgery Certifying Examination in 2012 and as an Examiner in 2014.
Confirmed Invited Speakers
Masanori Aikawa PhD
Director, Center for Interdisciplinary Cardiovascular Sciences, Yoshihiro Miwa Associate Chair, Brigham and Women’s Hospital, Associate Professor of Medicine, Harvard Medical School, Boston, MA, USA, pathogenesis of atherosclerosis
Kayla Bayless PhD
Associate Professor Department of Molecular and Cellular Medicine, College Station, TX, USA, extracellular matrix biology
Francois Bernier MD
Associate Professor, Medical Genetics, Director of the Clinical Genetics Unit, University of Calgary and Alberta Children’s Hospital, Alberta, Canada. Research: genetics, sequencing, rare disease, childhood neurodevelopmental disorders, maternal and child health, congenital anomalies, aortopathies
Emma Birks MD, PhD, FRCP
Professor, Medicine, Physiology and Biophysics, Surgery, Director, Heart Failure, Transplant, and Mechanical Support Program, Cardiovascular Innovation Institute, University of Louisville, Louisville, KY, USA. research: artificial organs and circulatory assist devices
Lauren Black PhD
Assistant Professor, Department of Biomedical Engineering, Tufts University, Medford, MA, USA. Research: myocardium repair, biophysical signaling mechanisms in healthy and diseased myocardium, mechanical stress/strain, electrical stimulation, cell-cell and cell-matrix interactions.
Andy Campbell PE
Vice President, Research and Development, Edwards Lifesciences, Irvine, CA, USA. Focus: development of surgical valve technology
Paul Fedak MD, PhD, FRCSC
Associate Professor, Department of Cardiac Sciences, University of Calgary; Cardiac Surgeon, Alberta Health Services, Surgical Heart Failure Program, Libin Cardiovascular Institute of Alberta, Calgary, AB Canada, advanced heart disease surgical therapies, regenerative medicine
Steven Greenway MD, MSc
Assistant Professor and Paediatric Cardiologist, Departments of Paediatrics, Cardiac Sciences, and Biochemistry & Molecular Biology, Cumming School of Medicine, University of Calgary and Alberta Children’s Hospital, Alberta, Canada. Research: diagnostic genomics, next-generation sequencing, congenital heart disease, transplantation, stem cells, immunosuppression of microbiome, metabolic cardiomyopathies
Rachael Hagan, MSc
Senior Program Director, Coulter Translational Partnership Program, Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology College of Engineering and Emory School of Medicine, Atlanta, Georgia, USA. Interests: medical product marketing, regulatory affairs, technology transfer, commercialization, entrepreneurship.
Coulter Program Manager, Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology College of Engineering and Emory School of Medicine, Atlanta, Georgia
Igor Kovalchuk PhD
Professor, Biological Sciences, University of Lethbridge, Alberta, Canada. Research: epigenetics, plant response to pathogen stress, DNA integration mechanisms, genome stability, chromatin remodeling
Olga Kovalchuk PhD
Professor, Board of Governors’ Research Chair, Biological Sciences, University of Lethbridge, Alberta, Canada. Research: epigenetics, genome stability, carcinogenesis, cancer treatment, oncogenic signaling.
Michael Laflamme MD, PhD
Associate Professor, Laboratory Medicine & Pathobiology, University of Toronto, Toronto, ON, Canada. Research: stem cells for cardiac repair, preclinical development of cardiac therapies
Richard Leask PhD
Associate Professor, William Dawson Scholar, Chemical Engineering, McGill University, Montreal, Quebec, Canada. Research: vascular mechanics, pathobiology of cardiovascular disease, biomedical devices, biomaterials, metabolomics of xenobiotics
Rebecca Levit MD
Assistant Professor of Medicine, Emory School of Medicine, Atlanta, Georgia. Research: stem cells, cardiovascular disease, medical devices
Scott LeMaire MD
Director of Research and Professor, Division of Cardiothoracic Surgery, Vice Chair for Research-Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA, thoracic aortic repair, genetic factors, and pathobiology
Joy Lincoln PhD
Associate Professor, Center for Cardiovascular Research, Nationwide Children’s Hospital, Columbus, Ohio, USA, molecular and cellular processes for heart valve structures
Randy Moore MD MSc FRCSC FACS
Associate Professor, Vascular Surgery, Libin Cardiovascular Institute, University of Calgary, Vascular and Endovascular Surgeon, Alberta Health Services, Peter Lougheed Centre, Calgary, AB Canada. Clinical and research interests: endovascular aortic and thoracoabdominal aneurysm repair, extracranial carotid artery disease, renovascular hypertension, peripheral arterial disease and bypass, and clinical research trials with interest in vascular hemodynamics
Dianna M. MIlewicz MD, PhD
President George H.W. Bush Chair of Cardiovascular Medicine, Director of the Division of Medical Genetics, Vice-Chair of the Department of Internal Medicine, University of Texas Medical School, Houston, TX, USA. Research: genetic predisposition to vascular diseases
Ed O'Brien MD, FRCPC
Chief of Cardiology and Professor, Department of Cardiac Sciences, Director, Vascular Biology Laboratory, Libin Cardiovascular Institute of Alberta, University of Calgary, Cumming School of Medicine, Calgary, AB, Canada. Research: atherosclerosis, heat shock protein 27, estrogens, PCSK9/p>
Rifat Pamukcu, President & CEO, Midway Pharmaceuticals, Philadelphia, Pennsylvania, Consultant to Wallace H. Coulter Foundation
Milica Radisic PhD, PEng
Professor, Institute of Biomaterials and Biomedical Engineering, Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada, cardiac tissue engineering and regenerative medicine
Frederick J. Schoen, M.D.,Ph.D.
Professor of Pathology and Health Sciences and Technology, Harvard Medical School, Executive Vice Chairman, Department of Pathology, Brigham and Women’s Hospital, Boston, MA, USA. Research and Clinical Interests: cardiac pathology, heart valve structure, cell/matrix biology, tissue engineering and calcification, development of heart valve replacements, transcatheter aortic valves, technology innovation, mentoring for physicians and scientists/engineers in translational research
To view the meeting program, click here
To view full schedule, click here
Wednesday, September 7
10:00 – 12:30: ISACB Executive Committee Meeting
1:00 – 3:00: Pre-Meeting Workshop: Developing a TEDMED-Style Research Presentation*
(see below for detailed information)
3:15 – 5:45: Pre-Meeting Workshop: Genomics for Cardiovascular Disease Assessment and Treatment*
(see below for detailed information)
6:00 – 8:00: Welcome Reception
8:00: Dinner on own
Thursday, September 8
7:00 – 8:00: Breakfast (included with registration)
8:00 – 8:10: Introduction to the Meeting
8:10 – 11:30: Arterial Remodeling: Bridging Molecular Mechanisms and Arterial Mechanics
11:30 – 12:30: Keynote Speaker: Ben Starnes, MD
12:30 – 1:30: Lunch (included with registration)
1:30 – 3:00: Technology Translation and Commercialization I
3:20 – 6:20: Valvular Heart Disease
6:30 – 8:30: Poster Session and Reception
8:30: Dinner on own
Friday, September 9
7:00 – 8:00: Breakfast (included with registration)
8:00 – 10:40: Frontiers in Heart Failure, Cardiac Assist and Regeneration
11:00 – 12:00: Technology Translation and Commercialization II
12:30 – 6:00: Excursions, options include white water rafting, glacier hikes, visiting town of Banff*
6:30 – 10:00: Conference Dinner including Keynote Speaker Stuart Hutchison, MD*
Saturday, September 10
7:00 – 8:00: Breakfast (included with registration)
8:00 – 8:30: ISACB Members Meeting
8:30 – 11:30: Platform Technologies & Biomaterials
11:45 – 12:45: Panel Discussion – Where are we going?
12:45: End of conference
*Requires additional registration
Pre-meeting Workshops Wednesday September 7, 2016
Max Bell 253 Banff Centre
Separate registration required
1:00-3:00 Developing a TEDMED-Style Research Presentation
Organizers: Jane Grande-Allen and Dianna Milewicz
Have you been inspired by the personal, compelling nature of TED and TEDMED talks? Do you wish you could present your work in a way that connects with your audience and distills your work into an uplifting story with lasting impact? Think how helpful this skill would be in explaining your research to your friends, family, potential employers, or a funding agency!
The compelling nature of TED and TEDMED talks is not due to the inherent skills of the speaker. These skills are learned, but you have to start somewhere.
In this interactive workshop, trainees will take their presentation / research concepts through a transformation using the principles and instructions given to actual TEDMED and TED speakers, as described in the new book “TED Talks: The Official TED Guide to Public Speaking”. This interactive workshop will cover how to shape your message and how to deliver this message effectively on stage. At the end of the workshop, trainees will have the opportunity to present key aspects of their message.
3:15-5:45 Genomics and Epigenetics in a Dynamic Environment: Concepts, Techniques and Applications in Medicine
Sponsored by: The Alberta Epigenetics Network
Chairs: Francois Bernier, Steven Greenway, and Deborah Studer
Presenters: Francois Bernier, Igor Kovalchuk, Olga Kovalchuk, Steven Greenway, Richard Leask, and Dianna Milewicz
This workshop will cover current ‘omics and epigenetics technologies, advanced biomarkers, mechanobiology influences, applications in cancer and cardiovascular systems, and factors important for development of new technologies and successful translation to the clinic.