Member News 5/18


Elena Aikawa, MD, PhD of Harvard University Medical School had the following articles published out of her lab:

van der Valk DC*, van der Ven CFT*, Blaser MC*, Grolman JM,, Wu PJ, Fenton OS, Lee LH, Tibbitt MW, Andresen J, Wen JR, Ha AH, Buffolo F, van Mil A, Bouten CVC, Body SC, Mooney DJ, Sluijter JPG, Aikawa M, Hjortnaes JH, Langer RS, Aikawa E. Engineering a 3D-Bioprinted Model of Human Heart Valve Disease Using Nanoindentation-Based Biomechanics. Nanomaterials, in press. *These authors contributed equally.

Schlotter F, Halu A, Goto S, Blaser MC, Body SC, Lee LH, Higashi H, DeLaughter DM, Hutcheson JD, Vyas P, Pham T, Rogers MA, Sharma A, Seidman CE, Loscalzo J, Seidman JG, Aikawa M, Singh SA, Aikawa E

Spatiotemporal Multi-omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease.

Circulation. 2018;:ePub - PMID: 29588317

Itoh S, Mizuno K, Aikawa M, Aikawa E

Dimerization of sortilin regulates its trafficking to extracellular vesicles.

J Biol Chem. 2018;293(12):4532-4544 - PMID: 29382723 - PMCID: PMC5868269


Cynthia St. Hilaire, PhD of the University of Pittsburg recently had a review published in Frontiers in Cardiovascular Medicine:


Glenn Gaudette, PhD of Worcester Polytechnic Institute shares the following news:

Glenn was recently named as an AIMBE fellow.

A story on work from his group was the 7th most popular story on National Geographic in 2017 (

 The Bill Nye Saves the World show will likely feature his groups work in the 3rd episode in season 3! ; The episode comes out on May 11th


Alexey Kamenskiy, PhD of the University of Nebraska Medical Center recently had a paper published in Arteriosclerosis, Thrombosis, and Vascular Biology :


Nicolas L’Heureux PhD of INSERM recently received the prestigious ERC Advanced grant from the European Research Council.  The title is “HUMAN TEXTILES: Human, Woven, Tissue-Engineered Blood Vessels (TEBV) Exclusively from Cell- Assembled Extracellular Matrix (CAM)”.


Joshua Hutcheson, PhD of Florida International University recently had the following papers published:

Bakhshian Nik A, Hutcheson JD, Aikawa E

Extracellular Vesicles As Mediators of Cardiovascular Calcification.

Front Cardiovasc Med. 2017;4:78 - PMID: 29322046


Hutcheson JD, Aikawa E

Extracellular vesicles in cardiovascular homeostasis and disease.

Curr Opin Cardiol. 2018;33(3):290-297 - PMID: 29465447


Pokhrel R, Gerstman BS, Hutcheson JD, Chapagain PP

In Silico Investigations of Calcium Phosphate Mineralization in Extracellular Vesicles.

J Phys Chem B. 2018;122(14):3782-3789 - PMID: 29519123

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